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Maternal serum folate and vitamin B12 concentrations in pregnancies associated with neural tube defects.

โœ Scribed by Molloy, A M; Kirke, P; Hillary, I; Weir, D G; Scott, J M


Book ID
115514465
Publisher
BMJ Publishing Group
Year
1985
Tongue
English
Weight
828 KB
Volume
60
Category
Article
ISSN
0003-9888

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While folate supplementation reduces the risk of recurrent neural-tube defects (NTD), both folate and cobalamin deficiencies may be independent risk-factors for neural-tube defects. Folate-dependence and impaired remethylation of homocysteine are implicated as mechanisms for NTD. There are few refer