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MATERNAL SERUM ALPHA-FETOPROTEIN AND EPITHELIAL TUMOUR MARKER CONCENTRATIONS ARE NOT INCREASED BY FETAL SACROCOCCYGEAL TERATOMA

✍ Scribed by P. KIRKINEN; S. HEINONEN; K. VANAMO; M. RYYNäNEN

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 383 KB
Volume: 17
Category: Article
ISSN: 0197-3851
DOI: 10.1002/(sici)1097-0223(199701)17:1<47::aid-pd19>3.0.co;2-i

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✦ Synopsis

Maternal serum alpha-fetoprotein (AFP) and total beta-human chorionic gonadotrophin (hCG) concentrations were measured at the 15th gestational week in ten pregnancies complicated by fetal sacrococcygeal teratoma. The findings corresponded to those in normal pregnancies. Similarly. third-trimester concentrations of cancer antigen 12-5, tumour-associated trypsin inhibitor, and the amino-terminal propeptide of type I11 procollagen in the maternal serum were not significantly elevated. Histologically mature and immature/malignant cases did not differ from each other as regards the above-mentioned parameters. This abnormality cannot be detected by maternal serum trisomy screening in the second trimester.

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