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Maternal microchimerism leads to the presence of interleukin-2 in interleukin-2 knock out mice: Implications for the role of interleukin-2 in thymic function

โœ Scribed by Lucile E. Wrenshall; Elliot T. Stevens; Deandra R. Smith; John D. Miller


Book ID
113527035
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
558 KB
Volume
245
Category
Article
ISSN
0008-8749

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Thymic rudiments of 14-day-old mouse embryos were put into organ culture in the presence of interleukin 2 (IL2) and PC.61, a monoclonal antibody that binds to the IL2 receptor (IL2R). After 5 and 7 days of culture, we found no influence of PC.61 on the growth of the thymus and the composition of the