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Maternal deprivation induces deficits in temporal memory and cognitive flexibility and exaggerates synaptic plasticity in the rat medial prefrontal cortex

✍ Scribed by Baudin, Aurélie; Blot, Kévin; Verney, Catherine; Estevez, Lucie; Santamaria, Julie; Gressens, Pierre; Giros, Bruno; Otani, Satoru; Daugé, Valérie; Naudon, Laurent

Book ID
119333603
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
405 KB
Volume
98
Category
Article
ISSN
1074-7427

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Maternal deprivation induces deficits in
Maternal deprivation induces deficits in temporal memory and cognitive flexibility and exaggerates synaptic plasticity in the rat medial prefrontal cortex
✍ Baudin, Aurélie; Blot, Kévin; Verney, Catherine; Estevez, Lucie; Santamaria, Jul 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 405 KB

Early life adverse events can lead to structural and functional impairments in the prefrontal cortex (PFC). Here, we investigated whether maternal deprivation (MD) alters PFC-dependent executive functions, neurons and astrocytes number and synaptic plasticity in adult male Long-Evans rats. The depri