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Maternal Alloantigens Promote the Development of Tolerogenic Fetal Regulatory T Cells in Utero

✍ Scribed by Mold, J. E.; Michaelsson, J.; Burt, T. D.; Muench, M. O.; Beckerman, K. P.; Busch, M. P.; Lee, T.-H.; Nixon, D. F.; McCune, J. M.

Book ID
126627587
Publisher
American Association for the Advancement of Science
Year
2008
Tongue
English
Weight
282 KB
Volume
322
Category
Article
ISSN
0036-8075

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## Abstract The gut is home to a large number of Treg, with both CD4^+^ CD25^+^ Treg and bacterial antigen‐specific Tr1 cells present in normal mouse intestinal lamina propria. It has been shown recently that intestinal mucosal DC are able to induce Foxp3^+^ Treg through production of TGF‐β plus re