Equation (9) on page 2233 should read: The equation following Eq. (10) on page 2233 should read: 4H%z(h/bc)g g = Nro4 In these equations, N is Avogadro's number.
Matching of single-strand breaks to form double-strand breaks in DNA
β Scribed by David Freifelder; Bruce Trumbo
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1969
- Tongue
- English
- Weight
- 731 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0006-3525
No coin nor oath required. For personal study only.
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## Abstract DNA doubleβstrand breaks (DSBs) are the most hazardous lesions arising in the genome of eukaryotic organisms, and yet occur normally during DNA replication, meiosis, and immune system development. The efficient repair of DSBs is crucial in maintaining genomic integrity, cellular viabili
## Abstract Two mechanisms are available for the repair of DNA doubleβstrand breaks (DSBs) in eukaryotic cells: homology directed repair (HDR) and nonβhomologous endβjoining (NHEJ). While NHEJ is not restricted to a particular phase of the cell cycle, it is incapable of accurately repairing DBSs th
## Abstract DNA DSBs are formed in normal human IMRβ90 cells during repair incubation after 100 and 300 JΒ·m^β2^ of UVL. By contrast, no DSBs are formed after UVL in human XPA cells that are unable to excise pyrimidine dimers. The DSBs are not due to immediate cell death since all the cells excluded