After almost a century of research, we have yet to solve the riddle of the mast cell. Whereas little was known about this cell for most of this time span, more facts have been gathered recently than seem to be reconcilable within a single unified concept of mast cell function. Anatomical observatio
Mast cells: function and contents
β Scribed by Lawrence B. Schwartz
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 993 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0952-7915
No coin nor oath required. For personal study only.
β¦ Synopsis
Mast cells, when activated, release a spectrum of mediators that initiate and modulate immediate-type hypersensitivity reactions. Recently is has been reported that expression of mast cell neutral proteases, specific markers of mast cells, is regulated by various growth factors. Human mast cells, like those in rodents, are now known to produce cytokines that modulate IgE production and inflammation.
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