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Mast cells contribute to double-stranded RNA-induced augmentation of airway eosinophilia in a murine model of asthma

✍ Scribed by Kan-o, Keiko ;Matsunaga, Yuko ;Fukuyama, Satoru ;Moriwaki, Atsushi ;Hirai-Kitajima, Hiroko ;Yokomizo, Takehiko ;Aritake, Kosuke ;Urade, Yoshihiro ;Nakanishi, Yoichi ;Inoue, Hiromasa ;Matsumoto, Koichiro


Book ID
120685125
Publisher
BMJ
Year
2013
Tongue
English
Weight
219 KB
Volume
14
Category
Article
ISSN
2052-4439

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## Abstract ## Background Eosinophilia plays the major role in the pathogenesis of asthma and correlates with the up‐regulation of eotaxin, which, together with interleukin (IL)‐5, is important for differentiation, chemo‐attraction, degranulation, and survival of eosinophils in local tissue. In a