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Mast cell chymase induces smooth muscle cell apoptosis by disrupting NF-κB-mediated survival signaling

✍ Scribed by Markus J. Leskinen; Hanna M. Heikkilä; Mei Y. Speer; Jukka K. Hakala; Mika Laine; Petri T. Kovanen; Ken A. Lindstedt


Book ID
118506375
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
581 KB
Volume
312
Category
Article
ISSN
0014-4827

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## Abstract Garcinol, obtained from __Garcinia indica__ in tropical regions, is used for its numerous biological effects. Its anti‐cancer activity has been suggested but the mechanism of action has not been studied in‐detail, especially there is no report on its action against breast cancer cells.