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Mass Spectroscopic Evidence on Inhibiting Effect of Maltosyl–β-Cyclodextrin on Insulin Self-association

✍ Scribed by Keiichi Tokihiro; Tetsumi Irie; Fumitoshi Hirayama; Kaneto Uekama

Book ID
118109969
Publisher
Pharmaceutical Press
Year
1996
Tongue
English
Weight
352 KB
Volume
2
Category
Article
ISSN
2042-7158

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Chlorpromazine is an antipsychotic agent with poor aqueous solubility. Complexation with SBE 7 -b-CD can aid intravenous delivery through increasing the apparent solubility of chlorpromazine. However, chlorpromazine has also been known to self-associate. This selfassociation can influence its capaci