Mass spectrometry of di-(2-ethylhexyl)phthalate metabolites
✍ Scribed by D. J. Harvan; J. R. Hass; P. W. Albro; M. D. Friesen
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 500 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1076-5174
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## Abstract Di‐(2‐ethylhexyl)phthalate (DEHP) was determined in environmental samples such as water and soil. DEHP was extracted from water samples using SPE, whereas for soils pressurized liquid extraction was applied as extraction method, using hexane/acetone (1:1, v/v) as extractant solvent. The
Di-(2-ethylhexyl)phthalate (DEHP) and its two major metabolites, mono-(2-ethyl-hexy1)phthalate (MEHP) and 2-ethylhexanol (EH), were evaluated for their ability to induce chromosomal damage in male Fischer 344 rats after oral administration. Dose levels, the highest of which represents one-tenth of t
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