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Mass Spectrometry in the Study of Non-enzymatic Glyco-oxidation of Proteins

✍ Scribed by Pietro Traldi; Donata Favretto; Roberta Seraglia; Annunziata Lapolla

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
275 KB
Volume
11
Category
Article
ISSN
0951-4198

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✦ Synopsis

Studies that have been performed by MALDI mass spectrometry in the field of non-enzymatic protein glyco-oxidation are briefly reviewed. The results obtained by in vitro and in vivo experiments demonstrate the power of this technique, which is able to give information on the number of sugar molecules condensed on specific proteins and, consequently, represents a new and specific diagnostic tool in diabetes control.

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