Mass Spectrometry in Biomolecular Sciences

✍ Scribed by Giovanni Sindona (auth.), Richard M. Caprioli, Antonio Malorni, Giovanni Sindona (eds.)

Publisher: Springer Netherlands
Year: 1996
Tongue: English
Leaves: 530
Series: NATO ASI Series 475
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

Mass Spectrometry in the Biological Sciences covers the most recent technological and applied developments in the area, including both ionization techniques and ion analysis. It introduces and reviews some of the newer ionization methods, describes the major instrumentation involved in mass analysis, and presents the scope of the technology in biology, medicine, and environmental science. Specific examples are given for a number of topics. It also deals with recent achievements in the on-line combination of separation techniques such as gas chromatography, liquid chromatography, and supercritical fluid technology.

✦ Table of Contents

Front Matter....Pages i-xxi
Front Matter....Pages 1-1
Ion Formation by Fast Atom Bombardment Mass Spectrometry....Pages 3-32
Matrix-Assisted Laser Desorption-Ionization (MALDI) Mass Spectrometry of Biological Molecules....Pages 33-49
Matrix-Assisted Laser Desorption Mass Spectrometry on a Magnetic Sector Instrument Fitted With an Array Detector....Pages 51-60
Electrospray Ionization Mass Spectrometry: Protein Structure....Pages 61-88
Applications of Quantum Chemistry in Mass Spectrometry....Pages 89-102
Proton Affinities and Intrinsic Basicities of Alanine and Glycine Studied by Means of AM1 and PM3 Methods....Pages 103-108
Front Matter....Pages 109-109
Energy—Isochronous Time—of—Flight Mass Spectrometers....Pages 111-146
The Detection of High Mass-to-Charge Biological Ions by Fourier Transform Mass Spectrometry: Issues and Routes for Instrument Improvement....Pages 147-175
Quadrupole Mass Filters, Quadrupole Ion Traps and Fourier Transform Ion Cyclotron Resonance Spectrometers....Pages 177-200
Energy Shifts in Collisional Activation....Pages 201-259
Hybrid Instruments of Unusual Geometry....Pages 261-270
Front Matter....Pages 271-271
Continuous-Flow Fast Atom Bombardment Mass Spectrometry: Applications to Dynamic Systems....Pages 273-297
Hybrid Tandem Mass Spectrometry of Peptides....Pages 299-315
Mass Spectrum in the Study of Advanced Glycation End Products....Pages 317-349
Nucleic Acids: Overview and Analytical Strategies....Pages 351-379
Monitoring of Human Exposure to Xenobiotics;....Pages 381-395
The Role of Mass Spectrometry in Biomonitoring Exposure to Carcinogens....Pages 397-415
Characterization Of Ceramide Mixtures by Fast Atom Bombardmentand Tandem Mass Spectrometry....Pages 417-428
Bioorganic Studies of a New Photoreceptor Structure....Pages 429-434
Front Matter....Pages 435-435
Gas Chromatography and Mass Spectrometry Coupling....Pages 437-460
Front Matter....Pages 435-435
Recent Developments in Combined Supercritical Fluid Chromatography/Mass Spectrometry (SFC/MS)....Pages 461-474
GC-MS Analysis of Volatile Compounds of Mesir....Pages 475-482
The Application of Mass Spectrometry to Food and Nutrition Research....Pages 483-517
Back Matter....Pages 517-523

✦ Subjects

Analytical Chemistry; Biochemistry, general; Ecotoxicology

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