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Mass spectrometry-based protein assays for in vitro diagnostic testing

✍ Scribed by Nedelkov, Dobrin

Book ID
111950261
Publisher
Expert Reviews
Year
2012
Tongue
English
Weight
358 KB
Volume
12
Category
Article
ISSN
1473-7159

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A sensitive assay using high-performance liquid chromatography tandem mass spectrometry (MS/MS) has been established for the quantitative analysis of cytochrome P450 form-specific activities using warfarin as a probe substrate. Four metabolites, 6-, 7-, 8-, and 10-hydroxywarfarin, were chromatograph