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Mass-spectrometric study of phthalazone, phthalazthione, and their methylation products

✍ Scribed by A. M. Zyakun; K. V. Grablyauskas; A. N. Kost; V. I. Zaretskii; N. S. Vul'fson


Book ID
112423588
Publisher
Springer
Year
1970
Tongue
English
Weight
464 KB
Volume
19
Category
Article
ISSN
1573-9171

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Gas chromatographic and mass spectrometr
✍ K. K. Midha; D. V. C. Awang; I. J. McGilveray; J. Kleber πŸ“‚ Article πŸ“… 1976 πŸ› John Wiley and Sons 🌐 English βš– 657 KB

Gas chromatographic analysis of the products of reaction of diazomethane with tolbutamide and chlorpropamide indicates the formation of three compounds in both cases. As expected, N-methylation (at sulfonamide nitrogen) is the predominant reaction; minor amounts of O-methylated product are also obse