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Mass spectrometric studies of phosphodiesters linked to oxysterols and nucleosides, a family of biologically potent oxygenated sterols

✍ Scribed by Xavier Pannecoucke; Alain Van Dorsselaer; Bang Luu


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
348 KB
Volume
27
Category
Article
ISSN
1076-5174

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✦ Synopsis


Negative-ion fast atom bombardment mass spectra of five compounds resulting from combinations between oxysterols and nucleoside analogues linked by phosphodiester bonds are presented and interpreted. This method seems to be the most appropriate for elucidating the structure of these complex, labile and non-volatile phosphatecontaining molecules which exhibit important antitumour and/or immunosuppressive activities.