MASS SPECTROMETRIC STUDIES OF 3-SUBSTITUTED-5-AMINO-1,3,4-THIADIAZOLIN-2-ONES
โ Scribed by Lee, Un Chul; Lee, Won; Kim, Yun Je; Park, Song Ja; Ra, Do Young; Cho, Nam Sook
- Book ID
- 126588334
- Publisher
- Taylor and Francis Group
- Year
- 1998
- Tongue
- English
- Weight
- 395 KB
- Volume
- 139
- Category
- Article
- ISSN
- 1042-6507
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## Abstract Acylation of 5โaminoโ3__H__โ1,3,4โthiadiazolinโ2โone (2) was undertaken selectively at either the 3โNH position or at 5โamino group depending on reaction conditions. The 3โNH is highly acidic and acylation takes place with acid anhydrides at this position in high yields in the presence
## Abstract 5โAminoโ2โacylโ1,2,4โthiadiazolinโ3โones 2โ1 can be synthesized from 5โaminoโ2__H__โ1,2,4โthiadiazolinโ3โone (1โ1) __via__ a selective acylation with an acid anhydride in pyridine. The ^1^H nmr spectral characteristics of 5โaminoโ2โacylโ1,2,4โthiadiazolinโ3โones 2โ1 is in particular, co