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Mass spectrometric detection of peginesatide in human urine in doping control analysis

✍ Scribed by Ines Möller; Andreas Thomas; Philippe Delahaut; Hans Geyer; Wilhelm Schänzer; Mario Thevis


Book ID
118125497
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
399 KB
Volume
70
Category
Article
ISSN
0731-7085

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Human exposure to carcinogenic alkylating agents can lead to the formation of covalently bound adducts in DNA, some of which are excreted in urine as alkylated purines following DNA degradation and repair. Tandem mass spectrometric methods have been developed for the qualitative and quantitative det