Mass spectral studies on prostaglandins. IV—prostaglandin F2α
✍ Scribed by Gyula Horváth
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 747 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1076-5174
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F2-isoprostanes are considered to be novel markers of lipid peroxidation. To study the in vivo formation of F2-isoprostanes, an improved method was developed for isotope dilution assays involving gas chromatography/triple-stage quadrupole mass spectrometry (GC/MS/MS) including thin-layer chromatogra
A nonspecific liver esterase was found to not only catalyze the hydrolysis of the methyl ester of prostaglandin F2o (PGF2o) but also to catalyze the exchange of the carboxyl oxygen atoms with water leading to the production of [\*R02]PGF2a. when the enzymatic hydrolysis is carried out in H,rSO. The