Mass spectral studies on mesoionic imidazo [1,2-a] pyrid-2 and -3-one derivatives
β Scribed by Wayne K. Anderson; Alan E. Friedman
- Publisher
- John Wiley and Sons
- Year
- 1972
- Tongue
- English
- Weight
- 332 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1076-5174
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π SIMILAR VOLUMES
Fragmentation patterns resulting from electron impact ionization of 3-(2'-hydroxyethyl)quinoIin-2(l~ne, three of its monosubstituted derivatives and four of its disubstituted derivatives were studied. The molecular ion of quinolinone-2ethanol undergoes initial fragmentation with the loss of OH, H,O,
Hydrazonoyl bromides 1a-c react with 5-amino-3phenyl-1H-pyrazole, 5-amino-1H-1,2,4-triazole, 2aminopyridine, 2-aminopyrimidine, and 2-aminobenzimidazole to afford the corresponding imidazo[1,2-b]pyrazoles 10, imidazo[1,2-b]-1,2,4-triazoles 11, imidazo[1,2-a]pyridines 16, imidazo[1,2-a]pyrimidines 17
N-2-(3@-Phthalidyl)phthalazin-1-one was synthesized by the condensation of 2-carboxybenzaldehyde with hydrazine hydrate using polyphosphoric acid as catalyst and solvent. Its 1H and 13C NMR spectra were completely assigned utilizing the two-dimensional 1H-detected heteronuclear one-bond (HMQC) and m