Mass Spectral and Antimicrobial Studies of the Benzofuran Analog of Chloramphenicol
β Scribed by Hanamanthsa S. Bevinakatti; Virupax V. Badiger
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 213 KB
- Volume
- 314
- Category
- Article
- ISSN
- 0365-6233
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
1β(2βBenzofuranyl)β2β(dichloroacetamido)propaneβ1,3βdiol breaks down in a wellβdefined manner upon electron impact. The principal ions formed are characterised and the most plausible mechanism of their formation is discussed. The results of in vitro antibacterial and antifungal screening of the benzofuran analog of chloramphenicol as well as its two precursors are reported.
π SIMILAR VOLUMES
The predominant pathway in the mass-spectral fragmentation of 4-dimethylamino-and 4-azidochalcones under the influence of electron impact is cleavage of the aryl--CO and CO--.CH bonds and localization of the charge on the fragment with the lower ionization energy. The characteristic "chalcone" rearr
The electron impact induced fragmentations of seven methoxynaphthoflavones have been studied with the aid of low-and high-resolution measurements, metastable decompositions and isotope labelling using carbon-13 atoms. The retro Diels-Alder cleavage of the methoxynaphthoflavones is strongly influence
The electron impact induced fragmentations of the five possible naphthoflavones have been studied with the aid of low-and high-resolution measurements, metastable decompositions and isotope labelling using either deuterium or carbon-13 atoms. All compounds show both the direct expulsion of a CO resi