Characterization of paired helical filam
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Hanna Ksiezak-Reding; Joseph S. Wall
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Article
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2005
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John Wiley and Sons
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English
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## Abstract Paired helical filaments (PHFs) are abnormal twisted filaments composed of hyperphosphorylated tau protein. They are found in Alzheimer's disease and other neurodegenerative disorders designated as tauopathies. They are a major component of intracellular inclusions known as neurofibrill