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Maspin, p53, p63, and Ki-67 in epithelial lesions of the tongue: from hyperplasia through dysplasia to carcinoma

โœ Scribed by Marilena Vered; Irit Allon; Dan Dayan


Book ID
111255178
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
346 KB
Volume
38
Category
Article
ISSN
0904-2512

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Oral squamous cell carcinoma develops through a series of precancerous stages manifested at the microscopic level as epithelial dysplasia. Mutation of the p53 tumour suppressor gene is thought to be an important component of oral carcinogenesis. p53 regulates cell proliferation and DNA repair by inh