✦ LIBER ✦
Markonikov Hydration and Amination of 10-Undecenoic Acid and BF3-Catalysed Dimethyl Sulphoxide Oxidation of Its Methyl Epoxide
✍ Scribed by Osman, S. M. ;Qazi, G. A.
- Publisher
- John Wiley and Sons
- Year
- 1975
- Weight
- 344 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0931-5985
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✦ Synopsis
Abstract
10‐Hydroxy and 10‐aminoundecanoic acids are conveniently prepared by solvomercuration‐demercuration of 10‐undecenoic acid using THF‐water and acetonitrile as nucleophilic solvents respectively. BF~3~‐catalysed dimethyl sulphoxide oxidation of its methyl epoxide resulted in the formation of methyl 10‐keto‐11‐hydroxyundecanoate. Thus in the case of a terminal olefinic acid only one out of the two isomeric products is formed according to Markonikov direction in the above reactions.