Markers for the functional availability of cobalamin/folate and their association with neuropsychiatric symptoms in the elderly
✍ Scribed by Björn Hultberg; Anders Isaksson; Karin Nilsson; Lars Gustafson
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 71 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0885-6230
- DOI
- 10.1002/gps.439
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✦ Synopsis
Abstract
Cobalamin/folate deficiency is common in elderly subjects and may lead to psychiatric symptoms, but even more often it increases the severity of other organic and non‐organic mental diseases. This paper reviews the literature relevant for markers of cobalamin/folate status and their relation to neuropsychiatric symptoms in the elderly. Plasma homocysteine, a marker of cobalamin/folate status, is frequently increased in psychogeriatric patients. Among markers of cobalamin/folate status, plasma homocysteine shows the best association with neuropsychiatric dysfunction. Copyright © 2001 John Wiley & Sons, Ltd.