Markedly Chemoselective Hydrogenation with Retention of Benzyl Ester and N-Cbz Functions Using a Heterogeneous Pd-Fibroin Catalyst.

Highly Chemoselective Hydrogenation with

Highly Chemoselective Hydrogenation with Retention of the Epoxide Function Using a Heterogeneous Pd/C-Ethylenediamine Catalyst and THF

✍ Hironao Sajiki; Kazuyuki Hattori; Kosaku Hirota 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 147 KB 👁 1 views

In general, palladium ± carbon (Pd/C) catalyzed hydrogenation of epoxides affords the corresponding primary and secondary alcohols as a mixture. It has been found that the catalytic activity of a Pd/C ± ethylenediamine complex catalyst [Pd/C(en)] in the hydrogenolysis of epoxide functions is drastic