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Marked Reduction of Helicobacter pylori-Induced Gastritis by Urease Inhibitors, Acetohydroxamic Acid and Flurofamide, in Mongolian Gerbils

✍ Scribed by Toshihisa Ohta; Hideyuki Shibata; Toshihiko Kawamori; Masaki Iimuro; Takashi Sugimura; Keiji Wakabayashi

Book ID: 115588291
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 242 KB
Volume: 285
Category: Article
ISSN: 0006-291X
DOI: 10.1006/bbrc.2001.5229

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## Abstract Nuclear factor‐κB (NF‐κB) plays a major role in host inflammatory responses and carcinogenesis and as such is an important drug target for adjuvant therapy. In this study, we examined the effect of caffeic acid phenethyl ester (CAPE), an NF‐κB inhibitor, on __Helicobacter pylori__ (__H.