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Marine natural products: Cytotoxic spermidine derivatives from the soft coral sinularia brongersmai

โœ Scribed by Francis J. Schmitz; K.H. Hollenbeak; R.S. Prasad


Book ID
104246413
Publisher
Elsevier Science
Year
1979
Tongue
French
Weight
221 KB
Volume
20
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


Two new cytotoxic spermidine derivatives isolated from the Pacific soft coral Sinularia brongersmai have been identified as CH~(CR~)~-C(CH~)ECH-CO-NH(CH~)~-N(CH~)-(CH~)I,-N(CH~)~ and its dihydro analog by spectral methods combined with chemical conversions. Acid hydrolysis of the saturated amide followed by esterification yielded methyl 3-methyldodecanoate.


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