𝔖 Bobbio Scriptorium
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Marimastat fails again

✍ Scribed by Michael, Adam


Book ID
109826966
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
67 KB
Volume
17
Category
Article
ISSN
1087-0156

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The synthesis of analogues of the matrix metalloproteinase (MMP) inhibitor marimastat has been achieved in one-pot by a two step procedure involving an Ugi four-component reaction followed by hydroxylaminolysis of an acetonide.