Maps of receptor binding parameters in the human brain — a kinetic analysis of PET measurements
✍ Scribed by Gunnar Blomqvist; Stefan Pauli; Lars Farde; Lars Eriksson; Anders Persson; Christer Halldin
- Book ID
- 104969486
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 892 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0340-6997
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
11 C]raclopride binding to D2 dopamine receptors in the striatum is sensitive to drug-induced changes of endogenous dopamine concentration. We recently developed the new radioligand [ 11 C]FLB 457, which is suitable for positron emission tomography (PET) studies of extrastriatal D2 dopamine recepto
The anatomical localization of 5-HT(4) receptor mRNA and 5-HT(4) receptor protein was examined in sections of post-mortem human brain by in situ hybridization histochemistry and radioligand receptor autoradiography. In the in situ hybridization study, the highest levels of 5-HT(4) receptor mRNA were
The selective D2-dopamine receptor antagonist raclopride and its pharmacologically inactive (R)-enantiomer FLB472 were labelled with 11C and used in a study with positron emission tomography to examine the stereoselectivity of 11C-raclopride binding to central D2-dopamine receptors in three healthy