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Mapping the Sites for Selective Oxidation of Guanines in DNA

✍ Scribed by Senthilkumar, K.; Grozema, F. C.; Guerra, C. Fonseca; Bickelhaupt, F. M.; Siebbeles, L. D. A.

Book ID
127312410
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
40 KB
Volume
125
Category
Article
ISSN
0002-7863

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Photoinduced electron transfer between cyanobenzophenone substituted 2%-deoxyuridine (d CNBP U) and GG sequence on the same strand of duplex DNA was examined. It was found that 5%-GT CNBP U-3% was a most effective sequence for the generation of guanine radical cation, showing that DNA oligomers cont