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Mapping the receptor site for ergtoxin, a specific blocker of ERG channels

✍ Scribed by Liliana Pardo-López; Jesús Garcı́a-Valdés; Georgina B. Gurrola; Gail A. Robertson; Lourival D. Possani


Book ID
117103732
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
198 KB
Volume
510
Category
Article
ISSN
0014-5793

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Huperzine A (HUP-A), first isolated from the Chinese club moss Huperzia serrata, is a potent, reversible and selective inhibitor of acetylcholinesterase (AChE) over butyrylcholinesterase (BChE) (Life Sci . 54: 991-997). Because HUP-A has been shown to penetrate the blood-brain barrier, is more stabl