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Mapping the Interfaces of Protein−Nucleic Acid Complexes Using Cross-Saturation

✍ Scribed by Ramos, Andres; Kelly, Geoff; Hollingworth, David; Pastore, Annalisa; Frenkiel, Thomas


Book ID
126088395
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
257 KB
Volume
122
Category
Article
ISSN
0002-7863

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Model for the irreversible dissociation
✍ Timothy M. Lohman 📂 Article 📅 1983 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 923 KB

## Abstract We present a quantitative model for the irreversible dissociation kinetics of cooperatively bound nonspecific protein–nucleic acid complexes. The model assumes that the major pathway of dissociation is via singly contiguously bound protein that “peels” off the ends of clusters of bound