## Abstract A small fraction of the typical animal genome (<5% in humans) codes for the organism's collection of proteins, yet the study of protein coding sequences dominated the early years of genomics research. In the decade since the sequencing of complete eukaryotic genomes, however, genomic te
✦ LIBER ✦
Mapping the genome one molecule at a time — optical mapping
✍ Scribed by Samad, Akhtar H.; Cai, Wei Wen; Hu, Xinghua; Irvin, Benjamin; Jing, Junping; Reed, Jason; Meng, Xun; Huang, John; Huff, Edward; Porter, Brett
- Book ID
- 109794630
- Publisher
- Nature Publishing Group
- Year
- 1995
- Tongue
- English
- Weight
- 581 KB
- Volume
- 378
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/378516a0
No coin nor oath required. For personal study only.
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## Abstract Wrapping DNA into chromatin provides a wealth of regulatory mechanisms that ensure normal growth and development in eukaryotes. Our understanding of chromatin structure, including nucleosomes and non‐histone protein–DNA interactions, has benefited immensely from nuclease and chemical di