Mapping the autoimmunizing epitopes on acetylcholine receptors
β Scribed by Gillian Harcourt; Andy Jermy
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 430 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0167-5699
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π SIMILAR VOLUMES
Myasthenia gravis (MG) is a neuromuscular disorder of man caused by a humoral response to the acetylcholine receptor (AChR). Most of the antibodies in MG and in experimental autoimmune myasthenia gravis (EAMG) are directed to the extracellular portion of the AChR alpha subunit, and within it, primar
Myasthenia gravis (MG) is an autoimmune disease caused by T cell-dependent antibody-mediated reduction of acetylcholine receptors (AChR) at the neuromuscular junction. Immunization of animals with Torpedo californica AChR (TAChR) results in an experimental model of MG. We used the variable regions o