๐”– Bobbio Scriptorium
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Mapping the active site of meprin-A with peptide substrates and inhibitors

โœ Scribed by Wolz, Russell L.; Harris, Robert B.; Bond, Judith S.

Book ID
127343731
Publisher
American Chemical Society
Year
1991
Tongue
English
Weight
729 KB
Volume
30
Category
Article
ISSN
0006-2960

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New templates were designed and prepared which straddle the active site of HIV-1 protease. These templates were designed to be 'flexible scaffolds' upon which substituents could be appended to fill the pockets of HIV protease. The new templates prepared and analysed were 4-hydroxy-5H-furan-2-ones, 4