✦ LIBER ✦

Mapping of the spatial variation in alginate concentration in calcium alginate gels by magnetic resonance imaging(MRI)

✍ Scribed by Potter Kimberlee; Carpenter T. Adrian; Hall Laurence

Publisher: Elsevier Science
Year: 1993
Tongue: English
Weight: 453 KB
Volume: 246
Category: Article
ISSN: 0008-6215
DOI: 10.1016/0008-6215(93)84022-x

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✦ Synopsis

A series of homogeneous calcium alginate gels, prepared in the presence of anti-gelling ions, were used to produce a calibration curve relating the spin-spin relaxation time (T.J of the water protons in the gel to the concentration of alginate. This was then used to calculate the spatial variation of alginate concentration in an inhomogeneous calcium alginate gel from a T, map computed from a series of one-dimensional MR-projection images. The concentration gradient for alginate derived thereby compared favourably with that subsequently obtained by physical sectioning of the gel.

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The displacement of the sol/gel interface during the gelation of sodium alginate by calcium ions can be tracked in both one and two dimensions using magnetic resonance imaging . In the one-dimensional gelation experiments, the distance moved by the sol/gel interface was proportional to (time'/ 2), w