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Mapping of the regulatory type Iα and catalytic β subunits of cAMP-dependent protein kinase and interleukin 1α and 1β in the pig

✍ Scribed by C. Mellink; Y. Lahbib-Mansais; M. Yerle; J. Gellin

Publisher
Springer-Verlag
Year
1994
Tongue
English
Weight
784 KB
Volume
5
Category
Article
ISSN
0938-8990

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✦ Synopsis

The genes coding for the regulatory type Ic~ subunit (PRKAR1A) and the catalytic [3 subunit (PRKACB) of cAMP-dependent protein kinase and the genes for interleukin lc~ (IL1A) and interleukin 1[~ (IL1B) were localized in the pig by means of radioactive in situ hybridization. PRKAR1A was mapped to 12pl.4 and PRKARB to 6q3.1 --~ q3.3. The genes for IL1A and IL1B were both assigned to Chromosome (Chr) 3, in the region ql.2 --~ ql.3 and ql.1 --~ ql.4, respectively. The cDNA nucleotide sequences of these porcine genes were compared with those of human, mouse, and cattle. The location of the genes was discussed in relation to the position of their homologous loci in these mammalian species.

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