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Mapping of the methylation pattern of the MUC2 promoter in pancreatic cancer cell lines, using bisulfite genomic sequencing

✍ Scribed by Tomofumi Hamada; Masamichi Goto; Hideaki Tsutsumida; Mitsuharu Nomoto; Michiyo Higashi; Tamotsu Sugai; Shin-ichi Nakamura; Suguru Yonezawa

Book ID
116333507
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
370 KB
Volume
227
Category
Article
ISSN
0304-3835

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## Abstract Loss of p16^INK4a^ protein expression has frequently been related to DNA methylation in association with gene silencing. Although the methylation status of exon1Ξ± for p16^INK4a^ involvement in various cancers has been extensively analyzed, it has been pointed out that some inconsistenci