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Mapping of the interacting domains of hepatitis C virus core protein and the double-stranded RNA-activated protein kinase PKR

✍ Scribed by Xue-Bing Yan; Serena Battaglia; Delphine Boucreux; Zhi Chen; Christian Brechot; Nicole Pavio

Book ID: 116967850
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 796 KB
Volume: 125
Category: Article
ISSN: 0168-1702
DOI: 10.1016/j.virusres.2006.12.010

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## Abstract Chronic hepatitis B virus (HBV) infection is a major cause of hepatocellular carcinoma (HCC) in Asia. Double‐stranded RNA (dsRNA)‐activated protein kinase (PKR) is an interferon‐induced, serine/threonine protein kinase. Recent studies have suggested that PKR is involved in the pathogene