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Mapping of the Fv-4 mouse gene controlling resistance to murine leukemia viruses

✍ Scribed by Hidetoshi Ikeda; Hidetoshi Sato; Takeshi Odaka

Publisher
John Wiley and Sons
Year
1981
Tongue
French
Weight
392 KB
Volume
28
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

Fv‐4, a gene controlling susceptibility to ecotropic murine leukemia viruses, was linked to both Pre‐1 (prealbumin) and Igh‐1 (immunoglobulin heavy‐chain constant region) loci on chromosome 12 in mice. The gene order was Fv‐4‐Pre‐1‐Igh‐1, and the estimated frequency of recombination between Fv‐4 and Pre‐1 was about 20%.

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