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Mapping of brain function after MPTP-induced neurotoxicity in a primate Parkinson's disease model

✍ Scribed by Anna-Liisa Brownell; Kelly Canales; Y.Iris Chen; Bruce G Jenkins; Christopher Owen; Elijahu Livni; Meixiang Yu; Francesca Cicchetti; Rosario Sanchez-Pernaute; Ole Isacson

Book ID
119586248
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
518 KB
Volume
20
Category
Article
ISSN
1053-8119

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Long-term treatment with levodopa in Parkinson's disease results in the development of motor fluctuations, including reduced duration of antiparkinsonian action and involuntary movements, i.e., levodopa-induced dyskinesia. Cannabinoid receptors are concentrated in the basal ganglia, and stimulation