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Mapping of a First Locus for Autosomal Dominant Myxomatous Mitral-Valve Prolapse to Chromosome 16p11.2-p12.1

✍ Scribed by Sandra Disse; Eric Abergel; Alain Berrebi; Anne-Marie Houot; Jean-Yves Le Heuzey; Benoît Diebold; Louis Guize; Alain Carpentier; Pierre Corvol; Xavier Jeunemaitre


Book ID
117853042
Publisher
American Society of Human Genetics
Year
1999
Tongue
English
Weight
252 KB
Volume
65
Category
Article
ISSN
0002-9297

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A new locus for Parkinson's disease (PAR
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## Abstract We performed genomewide linkage analysis of a Japanese family with autosomal dominant parkinsonism, which exhibits clinical features compatible with those of common Parkinson's disease. Parametric two‐point linkage analysis yielded a highest log odds (LOD) score of 4.32 at D12S345 (12p1