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Mapping complex disease traits with global gene expression

✍ Scribed by Cookson, William; Liang, Liming; Abecasis, Gonçalo; Moffatt, Miriam; Lathrop, Mark

Book ID
109952944
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
433 KB
Volume
10
Category
Article
ISSN
1471-0056

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## Abstract Models for complex and quantitative traits that involve multiple, possibly interacting, genes are described. Methods of linkage analysis are developed that utilize special features of these models, and their power is compared with that of simple genome scans that ignore these special fe