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Mapping by admixture linkage disequilibrium: advances, limitations and guidelines

✍ Scribed by O'Brien, Stephen J.; Smith, Michael W.

Book ID
109952157
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
389 KB
Volume
6
Category
Article
ISSN
1471-0056

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## Abstract We studied the feasibility of a novel approach to localize breast cancer susceptibility genes, using a low‐density genome‐wide panel of single‐nucleotide polymorphisms and taking advantage of large regions of linkage disequilibrium (LD) flanking Jewish disease genes in high‐risk cases.