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Mapping and sequencing rat dishevelled-1: a candidate gene for cerebral ischaemic insult in a rat model of stroke

✍ Scribed by Robert P.J. De Lange; Karen Burr; James S. Clark; C. Domingo Negrin; M. Julia Brosnan; David M. St Clair; Anna F. Dominiczak; Duncan J. Shaw


Publisher
Springer
Year
2001
Tongue
English
Weight
318 KB
Volume
3
Category
Article
ISSN
1364-6745

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## Abstract We evaluated a role of hypoxia‐inducible factor‐1α (HIF‐1α) and its downstream genes in acute hyperglycemia‐induced hemorrhagic transformation in a rat model of focal cerebral ischemia. Male Sprague‐Dawley rats weighing 280–300 g (n = 105) were divided into sham, 90 min middle cerebral