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MAPK inactivation is required for the G2 to M-phase transition of the first mitotic cell cycle

✍ Scribed by Abrieu, A.


Book ID
111745107
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
279 KB
Volume
16
Category
Article
ISSN
0261-4189

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The proto-oncogenes c-fos and c-jun have been shown in numerous model systems to be induced within minutes of growth factor stimulation, during the Go/G1 transition. In this report we use the mitotic shake-off procedure to generate a population of highly synchronized Swiss 3T3 cells. We show that bo