MAO-B inhibitors for the treatment of Pa
π
Article
π
2002
π
John Wiley and Sons
π
English
β 88 KB
## INTRODUCTION BACKGROUND Early attempts to enhance dopaminergic neurotransmission through inhibition of one of dopamine's major metabolizing enzyme -monoamine oxidase (MAO) -were made soon after the discovery of the striatal dopaminergic deficit and the efficacy of L-dopa. 1 However, side-effect