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Many-membered Carbon Rings. II. A New Synthesis of Civetone and dl-Muscone

โœ Scribed by Blomquist, A. T.; Holley, Robert W.; Spencer, R. D.


Book ID
121469762
Publisher
American Chemical Society
Year
1948
Tongue
English
Weight
354 KB
Volume
70
Category
Article
ISSN
0002-7863

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## Abstract Intramolecular __Grignard__โ€type reaction of the bromo lactones **3** and **8** affords the macrocycles **10, 11, 12** and **13, 14, 15**, respectively. More efficiently, **10** and **13** are obtained by intramolecular nucleophilic attack of the carbanions derived from the sulfonyl lac