β Scribed by R. J. Aitken (auth.), Professor Dr. med. Dr. h.c. Thomas Rabe, Professor Dr. med. Klaus Diedrich, Professor Dr. med. Thomas Strowitzki (eds.)
No coin nor oath required. For personal study only.
Our knowledge of reproductive medicine has expanded rapidly since the birth of Louise Brown, the first baby to be conceived by in vitro fertilization, which was performed by Professors Patrick Steptoe and Bob Edwards in Oldham, EngΒ land, in 1978. Hardly a year goes by without the development of a new or a modification of an existing method of assisted reproduction. Within a relatively short period, in vitro fertilization has been introduced into the treatment of female infertility. Intracytoplasmic sperm injection has also created new opportunities for the treatment of male infertility. The first edition of this book was published in 1996. In the second edition most of the chapters have been updated and additional interest is focused on intracytoplasmic sperm injection (ICSI) in view of the risk of malformations in newborns. This manual addresses the techniques of assisted reproduction that are availΒ able today. Competent authors from various centers present, in a concise way, their tried-and-tested procedures, so that the latter can be readily implemented. Due to different legal regulations, the scope of assisted reproduction is much more limited in Germany than in many other countries. For example, whereas only three embryos may be created and transferred in Germany, such restricΒ tions do not exist in several other European countries and the United States. Furthermore, heterologous fertilization, oocyte donation, and surrogate motherΒ hood are banned in Germany.
Front Matter....Pages I-XIX
Sperm Maturation and Oocyte Interaction....Pages 1-9
Menstrual Cycle: Follicular Maturation....Pages 11-21
Physiology of the Menstrual Cycle....Pages 23-77
Human Gonadotropins....Pages 79-132
Gonadotropin-Releasing Hormone: Agonists and Antagonists....Pages 133-164
Ovarian Stimulation for In Vitro Fertilization: Past and Present....Pages 165-195
Ovarian Hyperstimulation Syndrome....Pages 197-214
Luteal Phase: Physiology and Pharmacotherapy....Pages 215-222
An Andrological Approach to Assisted Reproduction....Pages 223-287
Mammalian Sex Preselection: Flow-cytometric Sorting of X and Y Spermatozoa Based on DNA Difference....Pages 289-302
Assessment of Oocyte and Early Embryo Morphology with Regard to Embryonic Development and the Outcome of Assisted Reproduction....Pages 303-320
Predicting Embryo Development....Pages 321-338
Cryoconservation: Sperms and Oocytes....Pages 339-375
Microinjection....Pages 377-387
In Vitro Fertilization....Pages 389-447
Evolution of Pregnancies and Initial Follow-up of Newborns Delivered after Intracytoplasmic Sperm Injection....Pages 449-460
Outcome of Children Born after In Vitro Fertilization (IVF) and Intracytoplasmic Sperm Injection (ICSI)....Pages 461-472
Laser in Assisted Reproduction....Pages 473-487
Assisting Reproduction with the Use of Donor Eggs....Pages 489-501
Oocyte Maturation In Vivo and In Vitro: Principles of Regulation....Pages 503-516
Preimplantation Diagnosis....Pages 517-527
Genetics in Assisted Reproduction β Basic Aspects and Clinical Perspectives....Pages 529-547
The Role of Endoscopy in Congenital Abnormalities: Diagnosis and Treatment....Pages 549-560
Endoscopic and Microsurgical Techniques in Reproductive Failure....Pages 561-574
Micro- and Macroconsequences of Ooplasmic Injections of Early Haploid Male Gametes....Pages 575-600
Artificial Intrauterine Insemination: Noninvasive Management of Subfertile Couples....Pages 601-656
Back Matter....Pages 657-665
Obstetrics/Perinatology
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